| Identification | Back Directory | [Name]
PAK | [CAS]
NoCAS | [Synonyms]
PAK
PAK-1
PAK-3
p65-PAK
S6/H4 kinase
P21-activated kinase 2
PAK1, active, GST tagged human
PYRIDOXINE-ALPHA-KETOGLUTARATE
CDC42/RAC effector kinase PAK-B
Serine/threonine-protein kinase PAK 1
Anti-PAK2 antibody produced in rabbit
Anti-PAK2, N-Terminal antibody produced in rabbit
Anti-PAK1, C-Terminal antibody produced in rabbit | [Molecular Formula]
C13H17NO8 | [MDL Number]
MFCD00239524 | [MOL File]
MFCD00239524 | [Molecular Weight]
315.28 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [form ]
buffered aqueous solution | [biological source]
rabbit | [Specific Activity]
63-85nmol/min·mg | [Major Application]
cell analysis |
| Hazard Information | Back Directory | [Uses]
cell analysis | [Biological Activity]
p21-activated kinases (PAKs) are serine/threonine kinases th at are activated by and are effectors of small GTPasescell division control protein 42 (CDC42) and Ras-related C3 botulinum toxin substrate (RAC). PAK1 is a key regulator of the actin cytoskeletonadhesion and cell motility. Inactive dimeric PAK1 is mainly cytosolic and interaction with the activators Cdc42-GTP and Rac1-GTP stimulates the kinase at the sites of cellular protrusions forming adhesions to the extracellular matrix. The protein has a role in numerous cellular processes and has been shown to be expressed in squamous non-small cell lung carcinomas. |
|
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
|