ChemicalBook--->CAS DataBase List--->189258-14-8

189258-14-8

189258-14-8 Structure

189258-14-8 Structure
IdentificationBack Directory
[Name]

ANTI-CASPASE-7
[CAS]

189258-14-8
[Synonyms]

MCH3
CMH-1
CASP7
ICE-7
LICE-2
ICE-LAP3
ANTI-MCH3
MCH-3ALPHA
ANTI-CASP7
ANTI-CMH-1
ANTI-ICE-7
ANTI-LICE-2
ANTI-ICE-LAP3
ANTI-MCH-3ALPHA
ANTI-HUMAN MCH-3
ANTI-HUMAN CASPASE-7
ANTI-CASPASE-7(C-18)
ANTI-ACTIVE CASPASE 7
ANTI-CASPASE-7 (HUMAN)
ANTISERUM TO CASPASE-7
ANTI-MCH3 (AB-3), HUMAN
ANTI-CASPASE-7 (ACTIVE)
ANTI-MCH3 (AB-2), HUMAN
ANTI-ICE-7 (AB-2), HUMAN
ANTI-ICE-7 (AB-3), HUMAN
ANTI-CMH-1 (AB-2), HUMAN
ANTI-CMH-1 (AB-3), HUMAN
ANTI-CASP7 (AB-2), HUMAN
ANTI-CASP7 (AB-3), HUMAN
ANTI-LEF-1 (AB-3), HUMAN
ANTI-LICE-2 (AB-2), HUMAN
ANTI-LICE-2 (AB-3), HUMAN
MONOCLONAL ANTI-CASPASE 7
ANTI-MCH3 (AB-2) MOUSE MAB
ANTI-ICE-7 (AB-2) MOUSE MAB
ANTI-ICE-LAP3 (AB-2), HUMAN
ANTI-ICE-LAP3 (AB-3), HUMAN
ANTI-CASP7 (AB-2) MOUSE MAB
ANTI-CMH-1 (AB-2) MOUSE MAB
ANTI-CASPASE-7 (AB-2), HUMAN
ANTI-LICE-2 (AB-2) MOUSE MAB
ANTI-CASPASE-7 (AB-3), HUMAN
ANTI-MCH-3ALPHA (AB-2), HUMAN
ANTI-MCH-3ALPHA (AB-3), HUMAN
ANTI-ICE-LAP3 (AB-2) MOUSE MAB
ANTISERUM TO CASPASE-7 (ACTIVE)
ANTI-CASPASE-7, HUMAN, (RABBIT)
ANTI-CASPASE-7 (AB-2) MOUSE MAB
ANTI-MCH-3ALPHA (AB-2) MOUSE MAB
ANTISERUM TO CASPASE-7(PURIFIED)
CASPASE-7 (AB-2) MONOCLONAL ANTIBODY
ANTI-MCH3 (AB-1) (186-198) RABBIT PAB
ANTI-CASPASE 7 (MCH-3/ICE-LAP3/CMH-1)
ANTI-ICE-7 (AB-1) (186-198) RABBIT PAB
ANTI-CMH-1 (AB-1) (186-198) RABBIT PAB
ANTI-CASP7 (AB-1) (186-198) RABBIT PAB
ANTI-LICE-2 (AB-1) (186-198) RABBIT PAB
POLYCLONAL ANTIBODY TO CASPASE-7 (ACTIVE)
ANTI-ICE-LAP3 (AB-1) (186-198) RABBIT PAB
ANTI-CASPASE-7 (AB-1) (186-198) RABBIT PAB
ANTI-MCH-3ALPHA (AB-1) (186-198) RABBIT PAB
Anti-Caspase 7 antibody produced in rabbit
Anti-Caspase-7 (ab2) antibody produced in rabbit
Anti-Caspase-7 (ab1) antibody produced in rabbit
Anti-Caspase 7, apoptosis-related cysteine peptidase
Monoclonal Anti-Caspase 7 antibody produced in rat
Anti-CASP7 (p20, Cleaved-Asp198) antibody produced in rabbit
[MDL Number]

MFCD01633625
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

buffered aqueous solution
[biological source]

rat
Safety DataBack Directory
[WGK Germany ]

-
Hazard InformationBack Directory
[Uses]

Monoclonal Anti-Caspase 7 antibody produced in rat is suitable for the following applications:
  • Immunoprecipitation
  • Microarray
  • Western blotting at a concentration of 2-4μg/mL using a whole extract of cultured human acute T cell leukemia Jurkat cells.
[General Description]

Caspase-7 is a apoptosis-related cysteine peptidase, commonly known as CASP7. It is a human protein encoded by the CASP7 gene. CASP7 is a member of the caspase (cysteine aspartate protease) family of proteins and is an executioner protein of apoptosis.
[Biochem/physiol Actions]

Caspase-3 and -7 plays a central role in the execution-phase of cell apoptosis. The gene for caspase 7 (also known as Mch3, CMH-1 and ICELAP3) encodes a “short” prodomain protein product of 35 kDa that belongs to the Ced3/ICE family of cysteine proteases. Caspase 7 undergoes acleavage upon activation by caspase-3, -9 and -10, and granzyme B, leading to p20 and p12 subunits. It is an important intracellular effector of granzyme B-mediated apoptosis and cytotoxic Tlymphocyte- induced cell killing in vivo. Monoclonal antibodies reacting specifically with caspase 7 are useful tools for the study of protease networks involved in development and regulation and governing the life and death of cells and tissues.
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