| Identification | Back Directory | [Name]
ANTI-CASPASE-7 | [CAS]
189258-14-8 | [Synonyms]
MCH3 CMH-1 CASP7 ICE-7 LICE-2 ICE-LAP3 ANTI-MCH3 MCH-3ALPHA ANTI-CASP7 ANTI-CMH-1 ANTI-ICE-7 ANTI-LICE-2 ANTI-ICE-LAP3 ANTI-MCH-3ALPHA ANTI-HUMAN MCH-3 ANTI-HUMAN CASPASE-7 ANTI-CASPASE-7(C-18) ANTI-ACTIVE CASPASE 7 ANTI-CASPASE-7 (HUMAN) ANTISERUM TO CASPASE-7 ANTI-MCH3 (AB-3), HUMAN ANTI-CASPASE-7 (ACTIVE) ANTI-MCH3 (AB-2), HUMAN ANTI-ICE-7 (AB-2), HUMAN ANTI-ICE-7 (AB-3), HUMAN ANTI-CMH-1 (AB-2), HUMAN ANTI-CMH-1 (AB-3), HUMAN ANTI-CASP7 (AB-2), HUMAN ANTI-CASP7 (AB-3), HUMAN ANTI-LEF-1 (AB-3), HUMAN ANTI-LICE-2 (AB-2), HUMAN ANTI-LICE-2 (AB-3), HUMAN MONOCLONAL ANTI-CASPASE 7 ANTI-MCH3 (AB-2) MOUSE MAB ANTI-ICE-7 (AB-2) MOUSE MAB ANTI-ICE-LAP3 (AB-2), HUMAN ANTI-ICE-LAP3 (AB-3), HUMAN ANTI-CASP7 (AB-2) MOUSE MAB ANTI-CMH-1 (AB-2) MOUSE MAB ANTI-CASPASE-7 (AB-2), HUMAN ANTI-LICE-2 (AB-2) MOUSE MAB ANTI-CASPASE-7 (AB-3), HUMAN ANTI-MCH-3ALPHA (AB-2), HUMAN ANTI-MCH-3ALPHA (AB-3), HUMAN ANTI-ICE-LAP3 (AB-2) MOUSE MAB ANTISERUM TO CASPASE-7 (ACTIVE) ANTI-CASPASE-7, HUMAN, (RABBIT) ANTI-CASPASE-7 (AB-2) MOUSE MAB ANTI-MCH-3ALPHA (AB-2) MOUSE MAB ANTISERUM TO CASPASE-7(PURIFIED) CASPASE-7 (AB-2) MONOCLONAL ANTIBODY ANTI-MCH3 (AB-1) (186-198) RABBIT PAB ANTI-CASPASE 7 (MCH-3/ICE-LAP3/CMH-1) ANTI-ICE-7 (AB-1) (186-198) RABBIT PAB ANTI-CMH-1 (AB-1) (186-198) RABBIT PAB ANTI-CASP7 (AB-1) (186-198) RABBIT PAB ANTI-LICE-2 (AB-1) (186-198) RABBIT PAB POLYCLONAL ANTIBODY TO CASPASE-7 (ACTIVE) ANTI-ICE-LAP3 (AB-1) (186-198) RABBIT PAB ANTI-CASPASE-7 (AB-1) (186-198) RABBIT PAB ANTI-MCH-3ALPHA (AB-1) (186-198) RABBIT PAB Anti-Caspase 7 antibody produced in rabbit Anti-Caspase-7 (ab2) antibody produced in rabbit Anti-Caspase-7 (ab1) antibody produced in rabbit Anti-Caspase 7, apoptosis-related cysteine peptidase Monoclonal Anti-Caspase 7 antibody produced in rat Anti-CASP7 (p20, Cleaved-Asp198) antibody produced in rabbit | [MDL Number]
MFCD01633625 |
| Hazard Information | Back Directory | [Uses]
Monoclonal Anti-Caspase 7 antibody produced in rat is suitable for the following applications:
- Immunoprecipitation
- Microarray
- Western blotting at a concentration of 2-4μg/mL using a whole extract of cultured human acute T cell leukemia Jurkat cells.
| [General Description]
Caspase-7 is a apoptosis-related cysteine peptidase, commonly known as CASP7. It is a human protein encoded by the CASP7 gene. CASP7 is a member of the caspase (cysteine aspartate protease) family of proteins and is an executioner protein of apoptosis. | [Biochem/physiol Actions]
Caspase-3 and -7 plays a central role in the execution-phase of cell apoptosis. The gene for caspase 7 (also known as Mch3, CMH-1 and ICELAP3) encodes a “short” prodomain protein product of 35 kDa that belongs to the Ced3/ICE family of cysteine proteases. Caspase 7 undergoes acleavage upon activation by caspase-3, -9 and -10, and granzyme B, leading to p20 and p12 subunits. It is an important intracellular effector of granzyme B-mediated apoptosis and cytotoxic Tlymphocyte- induced cell killing in vivo. Monoclonal antibodies reacting specifically with caspase 7 are useful tools for the study of protease networks involved in development and regulation and governing the life and death of cells and tissues. |
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Sigma-Aldrich
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Merck KGaA
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Creative Enzymes
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DeBioChem
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Alexis Corporation
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