| Chemical Properties | Back Directory | [Melting point ]
94-99°C | [Boiling point ]
704.2±60.0 °C(Predicted) | [density ]
1.252 | [storage temp. ]
Amber Vial, -20°C Freezer | [solubility ]
Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
13.13±0.46(Predicted) | [color ]
White to Pale Yellow | [Stability:]
Light Sensitive |
| Hazard Information | Back Directory | [Chemical Properties]
rac Lafutidine is Off-White Solid
| [Uses]
rac Lafutidine is a second generation histamine H2-receptor antagonist. Lafutidine is used as an antiulcerative.
| [Uses]
Second generation histamine H2-receptor antagonist. Antiulcerative. | [Definition]
ChEBI: Lafutidine is an organic molecular entity. | [in vivo]
(Z)-Lafutidine (Compound 16) stimulates mucin biosynthesis in rat gastric mucosa and this effect not directly due to histamine H2 receptor antagonism[1]. | Animal Model: | Eight- to nine-week-old male C57BL/6 mice weighing 20-24g[1] | | Dosage: | 3-30 mg/kg | | Administration: | P.o; twice for 6 days (5-FU: 50 mg/kg; i.p.;once daily) | | Result: | Reduced the severity of diarrhea during 5-FU treatment,in a mostly dose-dependent manner, and a significant effect was observed at a dose of 30 mg/kg.
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Alfa Chemistry
|
| Tel: |
+1 (201) 478-8534 |
| Website: |
www.alfa-chemistry.com |
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