| Identification | Back Directory | [Name]
19-Norlanost-5-en-11-one, 24-[(O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranosyl)oxy]-3-[(4-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-25-hydroxy-9-methyl-, (9β,10α,24R)- | [CAS]
2149606-15-3 | [Synonyms]
11-Oxoisomogroside V
19-Norlanost-5-en-11-one, 24-[(O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranosyl)oxy]-3-[(4-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-25-hydroxy-9-methyl-, (9β,10α,24R)- | [Molecular Formula]
C60H100O29 | [MOL File]
2149606-15-3.mol | [Molecular Weight]
1285.43 |
| Hazard Information | Back Directory | [Uses]
11-Oxoisomogroside V (compound 3) is a cucurbitacin isolated from the crude extract of Luo Han Guo. 11-Oxoisomogroside V activates the transcriptional activity of PGC-1α. In the luciferase experiment, the results showed that 10 μM and 20 μM 11-Oxoisomogroside V could increase the luciferase activity to 133.79% and 143.81%[1]. | [References]
[1] Niu B, et al. Cucurbitane Glucosides from the Crude Extract of Siraitia grosvenorii with Moderate Effects on PGC-1α Promoter Activity. J Nat Prod. 2017 May 26;80(5):1428-1435. DOI:10.1021/acs.jnatprod.6b01086 |
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