| Identification | Back Directory | [Name]
Benzeneethanamine, 4-iodo-2,5-dimethoxy-N-[(2-methoxyphenyl)methylene]-, [N(E)]- | [CAS]
2177287-33-9 | [Synonyms]
Benzeneethanamine, 4-iodo-2,5-dimethoxy-N-[(2-methoxyphenyl)methylene]-, [N(E)]- | [Molecular Formula]
C18H20INO3 |
| Hazard Information | Back Directory | [Description]
25I-NBOMe, a derivative of the serotonin 2A (5-HT2A) receptor agonist 2C-I, is 16-fold more potent than 2C-I with a Ki value of 0.044 nM for human 5-HT2A receptors.1,2 25I-NBOMe imine analog differs from 25I-NBOMe by having a double bond linking the N-(2-methoxybenzyl) group to 25I. The properties of this compound have not been evaluated. This product is intended for research and forensic applications. | [References]
1. Braden, M.R., Parrish, J.C., Naylor, J.C., et al. Molecular interaction of serotonin 5-HT2A receptor residues Phe3396.51 and Phe3406.52 with superpotent N-benzyl phenethylamine agonists Mol. Pharm. 70(6),1956-1965(2006).
2. Ettrup, A., Palner, M., Gillings, N., et al. Radiosysnthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET J. Nucl. Med. 51(11),1763-1770(2010). |
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