ChemicalBook--->CAS DataBase List--->2207-44-5

2207-44-5

2207-44-5 Structure

2207-44-5 Structure
IdentificationBack Directory
[Name]

2-[(5-Nitro-2-thiazolyl)thio]-benzothiazole
[CAS]

2207-44-5
[Synonyms]

BI-87G3
NPAS3-IN-1
JNK Inhibitor XI
BI-87G3 >=98% (HPLC)
JNK Inhibitor XI, BI-87G3
2-(5-Nitrothiazol-2-ylthio)benzo[d]thiazole
2-[(5-Nitro-2-thiazolyl)thio]-benzothiazole
Benzothiazole, 2-[(5-nitro-2-thiazolyl)thio]-
JNK Inhibitor XI, BI-87G3 - CAS 2207-44-5 - Calbiochem
[Molecular Formula]

C10H5N3O2S3
[MDL Number]

MFCD22666403
[MOL File]

2207-44-5.mol
[Molecular Weight]

295.36
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: soluble10mg/mL (clear solution)
[form ]

Yellow solid
[color ]

white to beige
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

25-36
[Safety Statements ]

25-45
[RIDADR ]

UN 2811 6.1 / PGIII
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Hazard InformationBack Directory
[Uses]

NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level[1].
[References]

[1] Li P, et al. Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT. Bioorg Chem. 2023 Oct;139:106676. DOI:10.1016/j.bioorg.2023.106676
Spectrum DetailBack Directory
[Spectrum Detail]

2-[(5-Nitro-2-thiazolyl)thio]-benzothiazole(2207-44-5)1HNMR
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