| Identification | Back Directory | [Name]
2-[(5-Nitro-2-thiazolyl)thio]-benzothiazole | [CAS]
2207-44-5 | [Synonyms]
BI-87G3 NPAS3-IN-1 JNK Inhibitor XI BI-87G3 >=98% (HPLC) JNK Inhibitor XI, BI-87G3 2-(5-Nitrothiazol-2-ylthio)benzo[d]thiazole 2-[(5-Nitro-2-thiazolyl)thio]-benzothiazole Benzothiazole, 2-[(5-nitro-2-thiazolyl)thio]- JNK Inhibitor XI, BI-87G3 - CAS 2207-44-5 - Calbiochem | [Molecular Formula]
C10H5N3O2S3 | [MDL Number]
MFCD22666403 | [MOL File]
2207-44-5.mol | [Molecular Weight]
295.36 |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
25-36 | [Safety Statements ]
25-45 | [RIDADR ]
UN 2811 6.1 / PGIII | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Uses]
NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization and regulates NPAS3 transcription by disrupting the heterodimerization of NPAS3 with ARNT at the cellular level[1]. | [References]
[1] Li P, et al. Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT. Bioorg Chem. 2023 Oct;139:106676. DOI:10.1016/j.bioorg.2023.106676 |
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