| Identification | Back Directory | [Name]
Rapamycin, 42-O-[4-[1-[32-[4-amino-3-(5-hydroxy-1H-indol-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-27-oxo-3,6,9,12,15,18,21,24-octaoxa-28-azadotriacont-1-yl]-1H-1,2,3-triazol-4-yl]butyl]- | [CAS]
2250059-52-8 | [Synonyms]
RMC-4627
Rapamycin, 42-O-[4-[1-[32-[4-amino-3-(5-hydroxy-1H-indol-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-27-oxo-3,6,9,12,15,18,21,24-octaoxa-28-azadotriacont-1-yl]-1H-1,2,3-triazol-4-yl]butyl]- | [Molecular Formula]
C93H141N11O23 | [Molecular Weight]
1781.17 |
| Hazard Information | Back Directory | [Uses]
RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth. | [References]
[1] Lee BJ, et al. Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth. Nat Chem Biol. 2021 Oct;17(10):1065-1074. DOI:10.1038/s41589-021-00813-7 |
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