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2259308-69-3

2259308-69-3 Structure

2259308-69-3 Structure
IdentificationBack Directory
[Name]

7-Quinazolinecarboxamide, 1-[(2-chloro-6-fluorophenyl)methyl]-1,2,3,4-tetrahydro-3,4-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-, (4R)-
[CAS]

2259308-69-3
[Synonyms]

STING agonist-10
7-Quinazolinecarboxamide, 1-[(2-chloro-6-fluorophenyl)methyl]-1,2,3,4-tetrahydro-3,4-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-, (4R)-
[Molecular Formula]

C25H20ClF4N3O2
[MOL File]

2259308-69-3.mol
[Molecular Weight]

505.89
Chemical PropertiesBack Directory
[Boiling point ]

581.9±50.0 °C(Predicted)
[density ]

1.393±0.06 g/cm3(Predicted)
[pka]

13.30±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

STING agonist-10 (Compound 91) is a potent small molecule cyclic urea activator of STING with the EC50 of 2600 nM. Activation of STING is a highly promising approach in immunotherapy[1].
[References]

[1] Sourav Basu, et al. The discovery of potent small molecule cyclic urea activators of STING. Eur J Med Chem. 2022 Feb 5;229:114087. DOI:10.1016/j.ejmech.2021.114087
2259308-69-3 suppliers list
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Company Name: TargetMol Chemicals Inc.  
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