ChemicalBook--->CAS DataBase List--->2380272-56-8

2380272-56-8

2380272-56-8 Structure

2380272-56-8 Structure
IdentificationBack Directory
[Name]

Phenol, 2-[6-amino-5-(1-piperazinyl)-3-pyridazinyl]-, hydrochloride (1:1)
[CAS]

2380272-56-8
[Synonyms]

Phenol, 2-[6-amino-5-(1-piperazinyl)-3-pyridazinyl]-, hydrochloride (1:1)
[Molecular Formula]

C14H18ClN5O
[MOL File]

2380272-56-8.mol
[Molecular Weight]

307.78
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

SMARCA-BD ligand 1 hydrochloride for PROTAC is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC[1].
[References]

[1] Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680. DOI:10.1038/s41589-019-0294-6
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