| Identification | Back Directory | [Name]
1H-Pyrrolo[2,3-b]pyridine, 3-(4-methoxyphenyl)-5-[1-(1-methyl-4-piperidinyl)-1H-pyrazol-4-yl]- | [CAS]
2403600-50-8 | [Synonyms]
HPK1-IN-25
1H-Pyrrolo[2,3-b]pyridine, 3-(4-methoxyphenyl)-5-[1-(1-methyl-4-piperidinyl)-1H-pyrazol-4-yl]- | [Molecular Formula]
C23H25N5O | [MOL File]
2403600-50-8.mol | [Molecular Weight]
387.48 |
| Hazard Information | Back Directory | [Uses]
HPK1-IN-25 (example 94) is a hematopoietic progenitor kinase 1 (HPK1) inhibitor with a enzymatic activity IC50 of 129 nM. HPK1-IN-25 has the potential for cancer research[1]. | [IC 50]
HPK1: 129 nM (IC50) | [References]
[1] Jing Li, et al. Pyrrolo [2, 3-b] pyridines or pyrrolo [2, 3-b] pyrazines as hpk1 inhibitor and the use thereof. WO2019238067A1. |
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