| Identification | Back Directory | [Name]
1-Piperidinepropanamide, 4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[2-[(1-oxo-2-propen-1-yl)amino]ethoxy]ethyl]- | [CAS]
2415537-51-6 | [Synonyms]
Con B-1
1-Piperidinepropanamide, 4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-5-(1-methylethoxy)phenyl]-N-[2-[2-[(1-oxo-2-propen-1-yl)amino]ethoxy]ethyl]- | [Molecular Formula]
C38H52ClN7O6S | [MOL File]
2415537-51-6.mol | [Molecular Weight]
770.38 |
| Hazard Information | Back Directory | [Uses]
ConB-1 is a potent and selective ALK inhibitor with low toxicity to normal cells[1]. | [References]
[1] Yan G, et al. Targeting Cysteine Located Outside the Active Site: An Effective Strategy for Covalent ALKi Design. J Med Chem. 2021 Feb 11;64(3):1558-1569. DOI:10.1021/acs.jmedchem.0c01707 |
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