| Identification | Back Directory | [Name]
9H-Pyrido[3,4-b]indole-9-acetonitrile, 7-methoxy-1-methyl- | [CAS]
241809-12-1 | [Synonyms]
AnnH31
9H-Pyrido[3,4-b]indole-9-acetonitrile, 7-methoxy-1-methyl- | [Molecular Formula]
C15H13N3O | [MOL File]
241809-12-1.mol | [Molecular Weight]
251.28 |
| Chemical Properties | Back Directory | [Boiling point ]
410.6±45.0 °C(Predicted) | [density ]
1.22±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
8.09±0.30(Predicted) | [color ]
Light brown to brown |
| Hazard Information | Back Directory | [Description]
AnnH31 is a novel potent DYRK1A Kinase Inhibitor. | [Uses]
AnnH31 is a Dyrk1A inhibitor (IC50: 81 nM). AnnH31 also inhibits MAO-A with an IC50 of 3.2 μM[1]. | [References]
[1] Rüben K, et al. Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors. PLoS One. 2015 Jul 20;10(7):e0132453. DOI:10.1371/journal.pone.0132453 |
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