| Identification | Back Directory | [Name]
1H-Pyrrolo[1,2-a]indole-1-acetic acid, 9-[(4-chlorophenyl)thio]-6-fluoro-2,3-dihydro-, (1R)- | [CAS]
2446042-90-4 | [Synonyms]
(R)-L 888607
1H-Pyrrolo[1,2-a]indole-1-acetic acid, 9-[(4-chlorophenyl)thio]-6-fluoro-2,3-dihydro-, (1R)- | [Molecular Formula]
C19H15ClFNO2S | [MDL Number]
MFCD34469406 | [MOL File]
2446042-90-4.mol | [Molecular Weight]
375.84 |
| Chemical Properties | Back Directory | [Boiling point ]
583.8±50.0 °C(Predicted) | [density ]
1.46±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.53±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
(R)-L 888607 is the isomer of L 888607 (HY-111271), and can be used as an experimental control. L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite[1]. | [References]
[1] Gervais FG, Identification of a potent and selective synthetic agonist at the CRTH2 receptor. Mol Pharmacol. 2005 Jun;67(6):1834-9. DOI:10.1124/mol.104.009068 |
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