| Identification | Back Directory | [Name]
Methanone, [4-(dimethylamino)-1-piperidinyl][2-[[4-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)phenyl]amino]-1H-benzimidazol-6-yl]- | [CAS]
2456295-60-4 | [Synonyms]
PI3K/mTOR Inhibitor-5
Methanone, [4-(dimethylamino)-1-piperidinyl][2-[[4-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)phenyl]amino]-1H-benzimidazol-6-yl]- | [Molecular Formula]
C32H40N10O3 | [MOL File]
2456295-60-4.mol | [Molecular Weight]
612.73 |
| Hazard Information | Back Directory | [Uses]
PI3K/mTOR Inhibitor-5 (compound 19a) is a potent and dual PI3K and mTOR inhibitor, with IC50 values of 86.9 nM and 14.6 nM, respectively[1]. | [References]
[1] Wu TT, Guo QQ, Chen ZL, et al. Design, synthesis and bioevaluation of novel substituted triazines as potential dual PI3K/mTOR inhibitors. Eur J Med Chem. 2020;204:112637. DOI:10.1016/j.ejmech.2020.112637 |
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