ChemicalBook--->CAS DataBase List--->2470242-33-0

2470242-33-0

2470242-33-0 Structure

2470242-33-0 Structure
IdentificationBack Directory
[Name]

HOIPIN-1
[CAS]

2470242-33-0
[Synonyms]

HOIPIN-1
JTP0819958
[Molecular Formula]

C17H14O4.Na
[MOL File]

2470242-33-0.mol
[Molecular Weight]

305.28
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to light yellow
Hazard InformationBack Directory
[Uses]

(E/Z)-HOIPIN-1 ((E/Z)-JTP-0819958) is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 value >2.8 μM. HOIPIN-1 inhibits LUBAC-mediated NF-kB activation.
[References]

[1] Katsuya K, et al. Small-molecule inhibitors of linear ubiquitin chain assembly complex (LUBAC), HOIPINs, suppress NF-κB signaling. Biochem Biophys Res Commun. 2019 Feb 12;509(3):700-706. DOI:10.1016/j.bbrc.2018.12.164
Spectrum DetailBack Directory
[Spectrum Detail]

HOIPIN-1(2470242-33-0)1HNMR
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