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2482310-18-7

2482310-18-7 Structure

2482310-18-7 Structure
IdentificationBack Directory
[Name]

11H-Indeno[1,2-b]quinoxalin-11-one, 2-[5-[2-(4-chlorophenyl)diazenyl]-4-methyl-2-thiazolyl]hydrazone
[CAS]

2482310-18-7
[Synonyms]

Apoptotic agent-2
11H-Indeno[1,2-b]quinoxalin-11-one, 2-[5-[2-(4-chlorophenyl)diazenyl]-4-methyl-2-thiazolyl]hydrazone
[Molecular Formula]

C25H16ClN7S
[MOL File]

2482310-18-7.mol
[Molecular Weight]

481.96
Chemical PropertiesBack Directory
[Boiling point ]

808.7±75.0 °C(Predicted)
[density ]

1.50±0.1 g/cm3(Predicted)
[pka]

6.26±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Apoptotic agent-2 (compound 14b) induces apoptosis by down-regulation of Bcl-2 and up-regulation of Bax and caspase-3. Apoptotic agent-2 exhibits anti-proliferative activities and can be used for cancer research[1].
[IC 50]

Bax; Caspase 3; Bcl-2
[References]

[1] Fayed EA, et al. In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies. Bioorg Chem. 2020 Jul;100:103951. DOI:10.1016/j.bioorg.2020.103951
2482310-18-7 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Website: http://www.cw-bio.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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