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2573304-30-8

2573304-30-8 Structure

2573304-30-8 Structure
IdentificationBack Directory
[Name]

KTX-582 intermediate-3
[CAS]

2573304-30-8
[Synonyms]

KTX-582 intermediate-3
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[Uses]

KTX-582 intermediate-3 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].
[References]

[1] Mainolfi, et al. Preparation of heterocycles as IRAK degraders and uses thereof. World Intellectual Property Organization, WO2020264499 A1. 2020-12-03.
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