| Identification | Back Directory | [Name]
Benzamide, 4-methyl-N-[1-(1-methylethyl)-1H-imidazol-4-yl]-3-[2-(3-pyridinyl)ethynyl]- | [CAS]
2574593-54-5 | [Synonyms]
c-ABL-IN-2
Benzamide, 4-methyl-N-[1-(1-methylethyl)-1H-imidazol-4-yl]-3-[2-(3-pyridinyl)ethynyl]- | [Molecular Formula]
C21H20N4O | [MOL File]
2574593-54-5.mol | [Molecular Weight]
344.41 |
| Hazard Information | Back Directory | [Uses]
c-ABL-IN-2 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-2 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) and cancer (extracted from patent WO2020260871A1, compound 25)[1]. c-ABL-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Rebecca PAUL, et al. New compounds and methods. Patent WO2020260871A1. |
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