| Identification | Back Directory | [Name]
9H-6,8a-Ethano-1H,6H-pyrrolo[1',2':3,4]imidazo[1,2-c]pyrimidin-1-one, 3-[[4-[3-chloro-4-(trifluoromethoxy)phenoxy]-3,5-difluorophenyl]methoxy]-7,8-dihydro- | [CAS]
2637485-12-0 | [Synonyms]
Lp-PLA2-IN-9
9H-6,8a-Ethano-1H,6H-pyrrolo[1',2':3,4]imidazo[1,2-c]pyrimidin-1-one, 3-[[4-[3-chloro-4-(trifluoromethoxy)phenoxy]-3,5-difluorophenyl]methoxy]-7,8-dihydro- | [Molecular Formula]
C25H19ClF5N3O4 | [MOL File]
2637485-12-0.mol | [Molecular Weight]
555.88 |
| Hazard Information | Back Directory | [Uses]
Lp-PLA2-IN-9 (compound 17), a tetracyclic pyrimidinone compound, is a potent Lp-PLA2 inhibitor with a pIC50 of 10.1 for rhLp-PLA2. Lp-PLA2-IN-9 has?the?potential?for?neurodegenerative related diseases research[1]. | [References]
[1] Qiong Xiao, et al. Tetracyclic pyrimidinone compounds, preparation method, composition and application thereof. CN112574221B. |
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