ChemicalBook--->CAS DataBase List--->2643308-61-4

2643308-61-4

2643308-61-4 Structure

2643308-61-4 Structure
IdentificationBack Directory
[Name]

Cyanine5.5 DBCO
[CAS]

2643308-61-4
[Synonyms]

Cyanine5.5 DBCO
Cyanine5.5 DBCO(PF6)
Dibenzocyclooctyne-Cy5.5(Synonyms:DBCO-Cy5.5
[Molecular Formula]

C61H63F6N4O2P
[MOL File]

2643308-61-4.mol
[Molecular Weight]

1029.17
Chemical PropertiesBack Directory
[solubility ]

good in DMF, DMSO, chlorinated organic solvents
[form ]

Solid
[color ]

Purple to purplish red
[Appearance]

dark colored solid
Hazard InformationBack Directory
[Description]

Strain promoted alkyne azide cycloaddition (SPAAC) between strained cycloalkynes and azides is a useful bioconjugation method that eliminates the need for copper catalyst necessary for classical CuAAC click chemistry.



Cyanine5.5 DBCO is a cyclooctyne product containing Cyanine5.5 fluorescent dye. This fluorophore is used in bioimaging, biodistribution studies, and microscopy.


Cyanine5.5 DBCO can be used to conjugate the fluorophore with various azides.


[Uses]

Dibenzocyclooctyne-Cy5.5 (DBCO-Cy5.5) is a fluorescent dye. Dibenzocyclooctyne-Cy5.5 can be used to syntheses calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging[1].
[References]

[1] Yong Geun Lim, et al. Calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging. Journal of Industrial and Engineering Chemistry. Volume 89, 25 September 2020, Pages 442-447
[Abs/Em Maxima]

684/710 nm
[Fluoresene quantum yield]

0.2
[Extinction Coefficient]

198000
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