| Chemical Properties | Back Directory | [Boiling point ]
643.1±55.0 °C(Predicted) | [density ]
1.509±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [solubility ]
DMF: 1 mg/ml
DMSO: 1 mg/ml
DMSO: PBS (pH 7.2) (1:2): 0.33 mg/ml | [pka]
2.35±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
PD-1/PD-L1-IN-36 (Compound 2k) is a PD-1/PD-L1 complex inhibitor (IC50: 15 nM). PD-1/PD-L1-IN-36 can be used for research of cancer immunotherapy[1]. | [References]
[1] Konieczny M, et al. Di-bromo-Based Small-Molecule Inhibitors of the PD-1/PD-L1 Immune Checkpoint. J Med Chem. 2020 Oct 8;63(19):11271-11285. DOI:10.1021/acs.jmedchem.0c01260 |
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| Company Name: |
ChemeGen
|
| Tel: |
18818260767 |
| Website: |
https://www.chemegen.com |
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