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2741190-31-6

2741190-31-6 Structure

2741190-31-6 Structure
IdentificationBack Directory
[Name]

Coumarin-Quinone Conjugate
[CAS]

2741190-31-6
[Synonyms]

Coumarin-Quinone Conjugate
[Molecular Formula]

C24H25NO6
[MOL File]

2741190-31-6.mol
[Molecular Weight]

423.46
Chemical PropertiesBack Directory
[Boiling point ]

602.226±55.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.254±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[solubility ]

DMSO: soluble
Ethanol: soluble
[pka]

2.769±0.20(predicted)
Hazard InformationBack Directory
[Uses]

Coumarin–quinone conjugate is a fluorescent substrate for NADH:ubiquinone oxidoreductases which consists of a coumarin fluorophore and a ubiquinone analog. Coumarin–quinone conjugate can be used to measure the kinetic parameters of AIFM2/FSP1 for researches such as ferroptosis[1].
[References]

[1] Doll S, et al. FSP1 is a glutathione-independent ferroptosis suppressor. Nature. 2019 Nov;575(7784):693-698. DOI:10.1038/s41586-019-1707-0
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