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PARP7-IN-15 (Compound 18) is a PARP7 inhibitor with IC50 of 0.56 nM, that has antitumor activity[1]. | [IC 50]
PARP7: 0.56 nM (IC50) | [References]
[1] Silong Zhang , et al. Exploring the structural-activity relationship of hexahydropyrazino[1,2-d]pyrido[3,2-b][1,4]oxazine derivatives as potent and orally-bioavailable PARP7 inhibitors. Eur J Med Chem. 2023 Oct 8:261:115836. DOI:10.1016/j.ejmech.2023.115836 |
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