| Identification | Back Directory | [Name]
INDEX NAME NOT YET ASSIGNED | [CAS]
2857037-69-3 | [Synonyms]
NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT
10H-1,3-Dioxolo[4,5-g]pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione, 14-(3-aminobicyclo[1.1.1]pent-1-yl)-7-ethyl-7-hydroxy-, (7S)- | [Molecular Formula]
C26H23N3O6 | [MOL File]
2857037-69-3.mol | [Molecular Weight]
473.48 |
| Chemical Properties | Back Directory | [Boiling point ]
850.5±65.0 °C(Predicted) | [density ]
1.65±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
11.17±0.20(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (compound I) is a topoisomerase I inhibitor，which can be delivered to cells through conjugated antibody targeting，and has good ADC activity in vivo and in vitro[1]. | [References]
[1] Andrew C. Phillips, et al. Anti-c-met antibody drug conjugates.WO2022232834. |
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