| Identification | Back Directory | [Name]
3-(4-Bromo-2-chloro-5-fluorophenyl)piperidine-2,6-dione | [CAS]
2924092-72-6 | [Synonyms]
CRBN ligand-110
3-(4-Bromo-2-chloro-5-fluorophenyl)piperidine-2,6-dione |
| Hazard Information | Back Directory | [Uses]
CRBN ligand-110 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC. | [IC 50]
Cereblon | [References]
[1] Mileti? N, et al. Workflow for E3 Ligase Ligand Validation for PROTAC Development. ACS Chem Biol. 2025 Feb 21;20(2):507-521. DOI:10.1021/acschembio.4c00812 |
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