| Identification | Back Directory | [Name]
3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione | [CAS]
2990057-63-9 | [Synonyms]
3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione | [Molecular Formula]
C11H9BrClNO2 | [MOL File]
2990057-63-9.mol | [Molecular Weight]
302.55 |
| Chemical Properties | Back Directory | [Boiling point ]
435.247±45.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.611±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
10.972±0.40(predicted) |
| Hazard Information | Back Directory | [Uses]
3-(5-Bromo-2-chlorophenyl)piperidine-2,6-dione is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC. | [IC 50]
Cereblon | [References]
[1] Mileti? N, et al. Workflow for E3 Ligase Ligand Validation for PROTAC Development. ACS Chem Biol. 2025 Feb 21;20(2):507-521. DOI:10.1021/acschembio.4c00812 |
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