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3032850-37-3

3032850-37-3 Structure

3032850-37-3 Structure
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[Name]

PROTAC BRD4 Degrader-22
[CAS]

3032850-37-3
[Synonyms]

PROTAC BRD4 Degrader-22
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[Uses]

PROTAC BRD4 Degrader-22 (Compd 44h) is a PROTAC-based BRD4 degrader, with a pDC50 (MOLT4, 24 h) of 9.2[1].
[References]

[1] Christian Steinebach, et al. Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs. J Med Chem. 2023 Oct 30. DOI:10.1021/acs.jmedchem.3c00851
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