ChemicalBook--->CAS DataBase List--->342877-55-8

342877-55-8

342877-55-8 Structure

342877-55-8 Structure
IdentificationBack Directory
[Name]

D-KLVFFA
[CAS]

342877-55-8
[Synonyms]

D-KLVFFA
D-LYS-D-LEU-D-VAL-D-PHE-D-PHE-D-ALA TRIFLUOROACETATE SALT
D-Alanine, D-lysyl-D-leucyl-D-valyl-D-phenylalanyl-D-phenylalanyl-
D-Lys-D-Leu-D-Val-D-Phe-D-Phe-D-Ala trifluoroacetate salt >=95% (HPLC)
[Molecular Formula]

C38H57N7O7
[MDL Number]

MFCD07784505
[MOL File]

342877-55-8.mol
[Molecular Weight]

723.9
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

H2O: >1 mg/mL
[form ]

powder
[color ]

white
[Sequence]

D-Lys-D-Leu-D-Val-D-Phe-D-Phe-D-Ala
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

D-KLVFFA is the inhibitor of Amyloid-β assembly, with the IC50 of 2.6 μM, that can be used in Alzheimer's disease study[1].
[References]

[1] Robert J Chalifour, et al. Stereoselective interactions of peptide inhibitors with the beta-amyloid peptide. J Biol Chem. 2003 Sep 12;278(37):34874-81. DOI:10.1074/jbc.M212694200
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