| Identification | Back Directory | [Name]
1-[(4-chlorophenyl)benzyl]-4-[(m-tolyl)methyl]piperazine hydrochloride | [CAS]
36236-67-6 | [Synonyms]
Einecs 252-932-4
1-[(4-chlorophenyl)benzyl]-4-[(m-tolyl)methyl]piperazine hydrochloride
1-(p-Chloro-alpha-phenylbenzyl)-4-(m-methylbenzyl)piperazine hydrochloride
Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-(m-methylbenzyl)-, hydrochloride
1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine/hydrochloride,(1:x) | [EINECS(EC#)]
252-932-4 | [Molecular Formula]
C25H28Cl2N2 | [MOL File]
36236-67-6.mol | [Molecular Weight]
427.409 |
| Chemical Properties | Back Directory | [Appearance]
White or yellowish powder or crystals;
slight odor. Insoluble in water and ether; very soluble in chloroform, pyridine, and acid-alcohol-water
mixture; slightly soluble in dilute acids and alcohol. | [Boiling point ]
577.93°C (rough estimate) | [density ]
1.0753 (rough estimate) | [refractive index ]
1.6300 (estimate) | [solubility ]
DMF: 5 mg/ml
DMSO: 0.1 mg/ml
Ethanol: 0.1 mg/ml | [Uses]
Medicine (antihistamine). |
| Hazard Information | Back Directory | [Chemical Properties]
White or yellowish powder or crystals;
slight odor. Insoluble in water and ether; very soluble in chloroform, pyridine, and acid-alcohol-water
mixture; slightly soluble in dilute acids and alcohol. | [References]
[1] V T TRAN S H S R S Chang. Histamine H1 receptors identified in mammalian brain membranes with [3H]mepyramine.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1978, 75 12: 6290-6294. DOI: 10.1073/pnas.75.12.6290
[2] CLAUDIA P. PASQUALE . Suppression by cetirizine of pleurisy triggered by antigen in actively sensitized rats[J]. European journal of pharmacology, 1992, 223 1: Pages 9-14. DOI: 10.1016/0014-2999(92)90811-h |
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