| Identification | Back Directory | [Name]
2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-7,8-dihydroxy-4a,8-dimethyl-, (4aR,7R,8R)- (9CI) | [CAS]
363610-34-8 | [Synonyms]
(4aR,7R,8R)-4,4a,5,6,7,8-Hexahydro-7,8-dihydroxy-4a,8-dimethyl-2(3H)-naphthalenone
2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-7,8-dihydroxy-4a,8-dimethyl-, (4aR,7R,8R)-
2(3H)-Naphthalenone, 4,4a,5,6,7,8-hexahydro-7,8-dihydroxy-4a,8-dimethyl-, (4aR,7R,8R)- (9CI) | [Molecular Formula]
C12H18O3 | [MOL File]
363610-34-8.mol | [Molecular Weight]
210.27 |
| Hazard Information | Back Directory | [Uses]
Oxyphyllenone A is an inhibitor of NO Synthase. Oxyphyllenone A inhibits the NO production in lipopolysaccharide-activated macrophages with an IC50 of 28 μM[1]. | [References]
[1] Muraoka O, et al. Absolute stereostructures of novel norcadinane- and trinoreudesmane-type sesquiterpenes with nitric oxide production inhibitory activity from Alpinia oxyphylla. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2217-20. DOI:10.1016/s0960-894x(01)00413-9 |
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