| Identification | Back Directory | [Name]
7-bromo-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one | [CAS]
37891-18-2 | [Synonyms]
7-bromo-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
2H-1,4-Benzodiazepin-2-one, 7-bromo-1,3-dihydro-3-hydroxy-5-phenyl- | [Molecular Formula]
C15H11BrN2O2 | [MOL File]
37891-18-2.mol | [Molecular Weight]
331.16 |
| Chemical Properties | Back Directory | [Melting point ]
202-203 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
517.6±50.0 °C(Predicted) | [density ]
1.61±0.1 g/cm3(Predicted) | [solubility ]
DMSO: Soluble: =10 mg/ml
Ethanol: Slightly soluble: 0.1-1 mg/ml | [pka]
10.94±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
3-Hydroxy desalkylgidazepam (compound 2) is the active metabolite of Gidazepam (HY-U00315) and Desalkylgidazepam (HY-W634748). | [References]
[1] Pavlovsky V I, et al. Synthesis, Affinity for Central Benzodiazepine Receptors, and Hypnosedative and Anxiolytic Properties of 3-Acyloxy-5-Aryl-7-Bromo-1, 2-Dihydro-3 H-1, 4-Benzodiazepin-2-Ones[J]. Pharmaceutical Chemistry Journal, 2019, 53: 207-211. |
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