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4281-28-1

4281-28-1 Structure

4281-28-1 Structure
IdentificationBack Directory
[Name]

5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one
[CAS]

4281-28-1
[Synonyms]

Sudachitin
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-
[Molecular Formula]

C18H16O8
[MOL File]

4281-28-1.mol
[Molecular Weight]

360.31
Hazard InformationBack Directory
[Uses]

Sudachitin, a polymethoxyflavone that can be isolated from Citrus sudachi, suppresses lipopolysaccharide-induced inflammatory responses in mouse macrophage-like RAW264 cells. Sudachitin can activate the p38MAPK pathway and inhibit the ERK1/2 pathway in HaCaT cells[1].
[Definition]

ChEBI: Sudachitin is an ether and a member of flavonoids.
[References]

[1] Keizo Yuasa, et al. Sudachitin, a polymethoxyflavone from Citrus sudachi, suppresses lipopolysaccharide-induced inflammatory responses in mouse macrophage-like RAW264 cells. Biosci Biotechnol Biochem. 2012;76(3):598-600. DOI:10.1271/bbb.110800
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