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454203-40-8

454203-40-8 Structure

454203-40-8 Structure
IdentificationBack Directory
[Name]

Sulfamic acid, [[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 4-[[(2S)-2,6-diamino-1-oxohexyl]amino]-2,6-bis(1-methylethyl)phenyl ester (9CI)
[CAS]

454203-40-8
[Synonyms]

ACAT-IN-10
Sulfamic acid, [[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 4-[[(2S)-2,6-diamino-1-oxohexyl]amino]-2,6-bis(1-methylethyl)phenyl ester (9CI)
[Molecular Formula]

C35H56N4O5S
[MOL File]

454203-40-8.mol
[Molecular Weight]

644.91
Chemical PropertiesBack Directory
[density ]

1.121±0.06 g/cm3(Predicted)
[pka]

1.83±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

ACAT-IN-10 is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor extracted from patent EP1236468A1, example 197. ACAT-IN-10 weakly inhibits NF-κB mediated transcription[1].
[References]

[1] Joseph Anthony Cornicelli, et al. Sulfonylaminocarbonyl derivatives for the treatment of nuclear factor-kappa B mediated diseases and disorders. EP1236468A1.
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