ChemicalBook--->CAS DataBase List--->51779-96-5

51779-96-5

51779-96-5 Structure

51779-96-5 Structure
IdentificationBack Directory
[Name]

dinervonylphosphatidylcholine
[CAS]

51779-96-5
[Synonyms]

24:1 (Cis) PC
dinervonylphosphatidylcholine
1,2-DINERVONOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;24:1 (CIS) PC
[Molecular Formula]

C56H108NO8P
[MDL Number]

MFCD00674316
[MOL File]

51779-96-5.mol
[Molecular Weight]

954.432
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

powder
[InChIKey]

REWNAIYQZZOESC-CGKZWXATSA-N
[SMILES]

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCCCCCCCC\C=C/CCCCCCCC)OCC[N+](C)(C)C
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS06,GHS08
[Signal word ]

Danger
[Hazard statements ]

H302-H315-H319-H331-H336-H351-H361d-H372-H412
[Precautionary statements ]

P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313
[WGK Germany ]

WGK 3
[Hazard Classifications]

Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 3
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1
STOT SE 3
Hazard InformationBack Directory
[Uses]

24:1 (Cis) PC (1,2-dinervonoyl-sn-glycero-3-phosphocholine) may be used in planar bilayer lipid membranes (BLMs) to study the effect of lipid chain length on single-channel properties of C-terminal colicin peptide (P178). It may also be used in planar bilayers to explore the single channel activities of BKCa (hSlo α-subunit) channels.
[Uses]

24:1 (Cis) PC has been used:
  • in the preparation of multivesicular liposomes (DepoFoam) formulation with protein or peptide drugs
  • in the formation of planar bilayer lipid membranes
  • for analyzing the phase transition of giant unilamellar dinervonoylphosphocholine (DNPC) vesicles by N-4-nitrobenz-2-oxa-1,3-diazol (NBD)-labelled fluorophore in confocal microscopy

[Uses]

Dinervonoyllecithin is used in a a cannulation device for administering ophthalmic delivery and ophthalmic drug compositions.
[Definition]

ChEBI: PC(24:1(15Z)/24:1(15Z)) is a 1,2-diacyl-sn-glycero-3-phosphocholine.
[General Description]

24:1 (Cis) PC (1,2-dinervonoyl-sn-glycero-3-phosphocholine) has two 24 carbon fatty acid chains, each having one cis double bond at the 15th carbon.
[Biochem/physiol Actions]

Phosphatidylcholine (PC) is essential for the structure and functions of eukaryotic membranes. PC is essential for very low-density lipoprotein synthesis in liver cells. PC is the substrate for sphingomyelin. PC is the major source of cell signaling molecules. PC is the structural component of many human parasites and helps in cell invasion.
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