| Chemical Properties | Back Directory | [Boiling point ]
357.0±27.0 °C(Predicted) | [density ]
1.258±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [solubility ]
Chloroform: Sparingly soluble: 1-10 mg/ml
Methyl Acetate: Soluble: =10 mg/ml |
| Hazard Information | Back Directory | [Uses]
O-2172, a carbacyclic analog, is a DAT inhibitor, with IC50 values of 47 nM and 7000 nM for DAT and SERT, respectively[1]. | [References]
[1] Peter C Meltzer, et al. Synthesis and evaluation of dopamine and serotonin transporter inhibition by oxacyclic and carbacyclic analogues of methylphenidate. J Med Chem. 2003 Apr 10;46(8):1538-45. DOI:10.1021/jm0205292 |
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