| Identification | Back Directory | [Name]
S-N(6)-methyladenosylhomocysteine | [CAS]
53228-06-1 | [Synonyms]
S-N(6)-methyladenosylhomocysteine
Adenosine, 5'-S-[(3S)-3-amino-3-carboxypropyl]-N-methyl-5'-thio- | [Molecular Formula]
C15H22N6O5S | [MOL File]
53228-06-1.mol | [Molecular Weight]
398.44 |
| Hazard Information | Back Directory | [Uses]
S-N6-Methyladenosylhomocysteine (Chart 1-1) is a potent inhibitor of histone methyltransferase DOT1L, with the IC50 of 0.29 μM. S-N6-Methyladenosylhomocysteine plays an important role in cancer research[1]. | [References]
[1] Baylor College of Medicine. Selective inhibitors of histone methyltransferase DOT1L. United States, US20140100184 A1 2014-04-10. |
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