ChemicalBook--->CAS DataBase List--->58160-95-5

58160-95-5

58160-95-5 Structure

58160-95-5 Structure
IdentificationBack Directory
[Name]

Propargylglycine
[CAS]

58160-95-5
[Synonyms]

propargylglycine
N-2-propyn-1-ylGlycine
Glycine,N-2-propyn-1-yl-
2-(Prop-2-ynylamino)acetic acid
Acetic acid, 2-(prop-2-ynylamino)-
[Molecular Formula]

C5H7NO2
[MOL File]

58160-95-5.mol
[Molecular Weight]

113.11
Chemical PropertiesBack Directory
[Melting point ]

243 °C (decomp)
[Boiling point ]

273.5±20.0 °C(Predicted)
[density ]

1.150±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

2.18±0.10(Predicted)
[color ]

Off-white to light yellow
[InChI]

InChI=1S/C5H7NO2/c1-2-3-6-4-5(7)8/h1,6H,3-4H2,(H,7,8)
[InChIKey]

XSJLQGMTIHCDSS-UHFFFAOYSA-N
[SMILES]

C(O)(=O)CNCC#C
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard InformationBack Directory
[Uses]

N-Propargylglycine is an orally active irreversible inhibitor of proline dehydrogenase (PRODH). N-Propargylglycine has antitumor activity and can be used in the study of neurodegenerative diseases[1].
[References]

[1] Scott GK, et al. N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties. Amino Acids. 2021 Dec;53(12):1927-1939. DOI:10.1007/s00726-021-03012-9
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