ChemicalBook--->CAS DataBase List--->62610-77-9

62610-77-9

62610-77-9 Structure

62610-77-9 Structure
IdentificationBack Directory
[Name]

METHACRIFOS
[CAS]

62610-77-9
[Synonyms]

DAMFIN
cga20168
oms-2005
Ai3-29266
Brn 1960498
METHACRIFOS
E-Methacrifos
trans-methacrifos
Methacrifos [iso]
Methacrifos (trans)
methacrifos (bsi,iso)
METHACRIFOS PESTANAL, 250 MG
Methacrifos@1000 μg/mL in Methanol
E-Methacrifos Solution in Methanol, 100μg/mL
methyl (E)-3-dimethoxyphosphanylsulfanyloxy-2-methyl-prop-2-...
(E)-o-2-Methoxycarbonylprop-1-enyl o,o-dimethyl phosphorothioate
METHYL (E)-3-(DIMETHOXYPHOSPHINOTHIONYLOXY)-2-METHYL-2-PROPENOATE
3-((dimethoxyphosphinothioyl)oxy)-2-methyl-2-propenoicacidmethylester,(e)
2-propenoicacid,3-((dimethoxyphosphinothioyl)oxy)-2-methyl-,methylester,(e
(E)-3-[(Dimethoxyphosphinothioyl)oxy]-2-methyl-2-propenoic acid methyl ester
2-Propenoic acid, 3-[(dimethoxyphosphinothioyl)oxy]-2-methyl-, methyl ester, (2E)-
[EINECS(EC#)]

630-448-8
[Molecular Formula]

C7H13O5PS
[MDL Number]

MFCD00078676
[MOL File]

62610-77-9.mol
[Molecular Weight]

240.21
Chemical PropertiesBack Directory
[Melting point ]

<25℃
[Boiling point ]

90℃
[density ]

1.250±0.06 g/cm3(Predicted)
[storage temp. ]

APPROX 4°C
[form ]

liquid
[Merck ]

13,5966
[Henry's Law Constant]

1.0×101 mol/(m3Pa) at 25℃, MacBean (2012)
[Major Application]

agriculture
environmental
[InChI]

1S/C7H13O5PS/c1-6(7(8)9-2)5-12-13(14,10-3)11-4/h5H,1-4H3/b6-5+
[InChIKey]

NTAHCMPOMKHKEU-AATRIKPKSA-N
[SMILES]

COC(=O)\C(C)=C\OP(=S)(OC)OC
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
[Signal word ]

Warning
[Hazard statements ]

H302-H317-H410
[Precautionary statements ]

P273-P280-P301+P312+P330-P302+P352
[Hazard Codes ]

Xn,N
[Risk Statements ]

22-43-50/53
[Safety Statements ]

36/37-60-61
[RIDADR ]

UN3077 9/PG 3
[WGK Germany ]

3
[RTECS ]

UD3335000
[HS Code ]

29201900
[Storage Class]

10 - Combustible liquids
[Hazard Classifications]

Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Skin Sens. 1
[Toxicity]

LD50 in rats (mg/kg): 678 orally; >3100 dermally (Wyniger)
Hazard InformationBack Directory
[Uses]

Grain protectant, insecticide, acaricide.
[Uses]

trans-Methacrifos is used as a pesticide used to protect crops and vegetation.
[Definition]

ChEBI: Methacrifos is an organic thiophosphate.
[Production Methods]

Methacrifos is commercially produced through specialized chemical synthesis thatm begins with the preparation of key intermediates such as dimethoxyphosphinothioyl chloride, which is then reacted with methyl methacrylate or related acrylic esters to form the active compound methyl (E)-3-dimethoxyphosphinothioyloxy-2-methylprop-2-enoate. The reaction is conducted in liquid phase at low temperatures to maintain product stability, followed by purification steps to ensure high-quality yield.
[Mechanism of action]

Stomach, contact and respiratory action with rapid knockdown and some residual activity. Acetylcholinesterase (AchE) inhibitor.
[Metabolism]

Methacrifos administered in animals is rapidly metabolized and excreted. The carboxy methyl ester bond is cleaved as well as the phosphoryl methyl and vinyl ester bonds. Oxidative desulfuration also occurs.
[Toxicity evaluation]

The acute oral LD50 for rats is 678 mg/kg. Inhalation LC50 (4 h) for rats is 2.2 mg/L air. NOEL (2 yr) for rats is 0.6 mg/kg b.w. daily. ADI is 6 μg/kg b.w.
[Pesticide Type]

Insecticide; Acaricide
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