| Identification | Back Directory | [Name]
chuangxinmycin | [CAS]
63339-68-4 | [Synonyms]
chuangxinmycin
Chuanghsinmycin
(-)-chuangxinmycin
(2R)-3,5-Dihydro-3β-methyl-2H-thiopyrano[4,3,2-cd]indole-2β-carboxylic acid
2H-Thiopyrano[4,3,2-cd]indole-2-carboxylic acid, 3,5-dihydro-3-methyl-, (2R,3S)-
(2R,3S)-3-methyl-3,5-dihydro-2H-sulfanylpyrano[4,3,2-cd]indol-2-carboxylic? acid | [Molecular Formula]
C12H11NO2S | [MOL File]
63339-68-4.mol | [Molecular Weight]
233.29 |
| Chemical Properties | Back Directory | [Boiling point ]
220.4°C (rough estimate) | [density ]
1.2503 (rough estimate) | [refractive index ]
1.6000 (estimate) | [pka]
3.82±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Chuangxinmycin is an antibiotic that can be isolated from Actinoplanes tsinanensis CPCC 200056. Chuangxinmycin exhibits both in vitro and in vivo antibacterial activities and can be utilized in infection research[1]. | [Definition]
ChEBI: A thiinoindole that is 3,5-dihydro-2H-thiino[4,3,2-cd]indole which is substituted at positions 2 and 3 by carboxy and methyl groups, respectively (the 2R,3S diastereoisomer). | [References]
[1] Shi Y, et al. Biosynthesis of antibiotic chuangxinmycin from Actinoplanes tsinanensis. Acta Pharm Sin B. 2018 Mar;8(2):283-294. DOI:10.1016/j.apsb.2017.07.005 |
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