| Identification | Back Directory | [Name]
4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[[(4-chlorobenzoyl)amino]thioxomethyl]amino]-5,6-dihydro- | [CAS]
637314-12-6 | [Synonyms]
ANO1-IN-2
4H-Cyclopenta[b]thiophene-3-carboxamide, 2-[[[(4-chlorobenzoyl)amino]thioxomethyl]amino]-5,6-dihydro- | [Molecular Formula]
C16H14ClN3O2S2 | [MOL File]
637314-12-6.mol | [Molecular Weight]
379.88 |
| Hazard Information | Back Directory | [Uses]
ANO1-IN-2 (Compound 10q) is a selective ANO1 channel blocker with an IC50 of 1.75 μM and 7.43 μM against ANO1 and ANO2, respectively. ANO1-IN-2 suppresses strongly proliferation of glioblastoma cells[1]. | [References]
[1] Choi SH, et al. Anti-glioma effects of 2-aminothiophene-3-carboxamide derivatives, ANO1 channel blockers. Eur J Med Chem. 2020 Dec 15;208:112688. DOI:10.1016/j.ejmech.2020.112688 |
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