ChemicalBook--->CAS DataBase List--->640281-90-9

640281-90-9

640281-90-9 Structure

640281-90-9 Structure
IdentificationBack Directory
[Name]

Valopicitabine
[CAS]

640281-90-9
[Synonyms]

NM283
Valopicitabine
valopicitabine (NM283)
L-Valine, 3'-ester with 2'-C-methylcytidine
[(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan-3-yl] (2S)-2-amino-3-methylbutanoate
[Molecular Formula]

C15H24N4O6
[MDL Number]

MFCD09838010
[MOL File]

640281-90-9.mol
[Molecular Weight]

356.377
Chemical PropertiesBack Directory
[Boiling point ]

548.4±60.0 °C(Predicted)
[density ]

1.54±0.1 g/cm3(Predicted)
[pka]

12.98±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

Treatment of chronic hepatitis C (HCV RNA polymerase inhibitor).
[in vivo]

Valopicitabine (NM283) (100 mg/kg; oral administration; Sprague-Dawley Rats) shows the Cmax, AUC, t1/2, and tmax were 3.624 μg/mL, 8.95 μg h/mL, 0.64 hours and 1 hour, respectively[2].
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