| Identification | Back Directory | [Name]
TERT-BUTYL-2-CHLORO-2-TRIMETHYLSILYLACETATE | [CAS]
66406-43-7 | [Synonyms]
REVBFXGFKCMPSR-UHFFFAOYSA-N
t-Butyl 2-Chloro-2-trimethylsilylacetate
TERT-BUTYL-2-CHLORO-2-TRIMETHYLSILYLACETATE
Acetic acid, 2-chloro-2-(trimethylsilyl)-, 1,1-dimethylethyl ester
tert-Butyl-2-chloro-2-trimethylsilylacetate**CUSTOMSYNTHESISPLEASEASK** | [Molecular Formula]
C9H19ClO2Si | [MDL Number]
MFCD01318406 | [MOL File]
66406-43-7.mol | [Molecular Weight]
222.78 |
| Hazard Information | Back Directory | [Application]
Tert-butyl-2-chloro-2-trimethylsilylacetate can olefinate enolizable ketones via the Peterson enolation reaction to generate functionalized tetrasubstituted olefins (α,β-unsaturated esters). | [Preparation]
Tert-butyl-2-chloro-2-trimethylsilylacetate is prepared from t-Butyl Chloroacetate by sequential reaction with Lithium Diisopropylamide and Chlorotrimethylsilane followed by aqueous workup and distillation. | [storage]
As this material is an activated alkyl halide, it must be considered a potential alkylating agent and lachrymator and handled with care and suitable protective clothing (e.g. gloves) in a fume hood. |
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