| Identification | Back Directory | [Name]
Flufiprole | [CAS]
704886-18-0 | [Synonyms]
Flufiprole
Flufiprole Solution, 1000ppm
1H-Pyrazole-3-carbonitrile, 1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5-[(2-methyl-2-propen-1-yl)amino]-4-[(trifluoromethyl)sulfinyl]- | [Molecular Formula]
C16H10Cl2F6N4OS | [MDL Number]
MFCD30272104 | [MOL File]
704886-18-0.mol | [Molecular Weight]
491.24 |
| Hazard Information | Back Directory | [Chemical Properties]
White loose powder, solubility (25℃,g/L): 0.02 in water, 260 in ethyl acetate, slightly soluble in petroleum ether, n-hexane, easily soluble in ethyl ether, acetone, trichloromethane, ethanol, DMF.Stable at room temperature, stable in water and organic solvents, and stable in weak acids, weak bases, and neutral media. Appearance of Butenaflumizole 5% emulsifiable concentrate is homogeneous transparent liquid. No visible suspension and precipitation. Emulsion stability (diluted 200 times) is qualified. | [Uses]
Flupiprole is an insecticide. | [Definition]
ChEBI: 1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5-[(2-methylprop-2-en-1-yl)amino]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile is a member of the class of pyrazoles that is 1H-pyrazole that is substituted at positions 1, 3, 4, and 5 by 2,6-dichloro-4-(trifluoromethyl)phenyl, cyano, (trifluoromethyl)sulfinyl, and (2-methylprop-2-en-1-yl)nitrilo groups, respectively. It is a dichlorobenzene, a member of (trifluoromethyl)benzenes, a member of pyrazoles, a nitrile and a sulfoxide. | [Production Methods]
Flufiprole is produced through a multi step synthesis that builds its pyrazole core and fluoroaryl substituents. The process begins with preparation of a substituted pyrazole intermediate, typically via condensation of hydrazine derivatives with beta diketones. This core is then functionalised by introducing trifluoromethyl and fluoroaryl groups through halogenation and coupling reactions. Subsequent steps involve acylation to form the amide linkage and controlled fluorination to achieve the final flufiprole structure. | [Mechanism of action]
Targets the γ-aminobutyric acid-dependent neurotransmission system of insects | [Pesticide Type]
Insecticide |
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