| Identification | Back Directory | [Name]
Pantoprazole sodiuM hydrate | [CAS]
718635-09-7 | [Synonyms]
Pantozol hydrate
Protonix hydrate
sodium,5-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]benzimidazol-1-ide,hydrate
5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt hydrate | [Molecular Formula]
C16H16F2N3NaO5S | [MDL Number]
MFCD08704580 | [MOL File]
718635-09-7.mol | [Molecular Weight]
423.367 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
H2O: ≥20mg/mL | [form ]
powder | [color ]
white to off-white | [Water Solubility ]
H2O: ≥20mg/mL | [InChI]
1S/C16H14F2N3O4S.Na.H2O/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16;;/h3-7,15H,8H2,1-2H3;;1H2/q-1;+1; | [InChIKey]
CGJRLPRCWSHOFU-UHFFFAOYSA-N | [SMILES]
O.[Na+].COc1ccnc(CS(=O)c2nc3cc(OC(F)F)ccc3[n-]2)c1OC |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [WGK Germany ]
1 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Uses]
Pantoprazole sodium hydrate has been used:
- as a standard in high-performance liquid chromatography (HPLC){58
- as a prazole to study its effects on prodrug activation and human immunodeficiency virus 1 (HIV-1) inhibition
- to study its effects on breast cancer resistance protein (BCRP) inhibitors in various in vitro membrane preparations from various cell lines
| [Biochem/physiol Actions]
Pantoprazole is a benzimidazole derivative,activated in acidic environment. It is useful in treating long term prophylaxis and acid-related disorders. |
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Sigma-Aldrich
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Merck KGaA
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www.sigmaaldrich.cn |
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