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739301-85-0

739301-85-0 Structure

739301-85-0 Structure
IdentificationBack Directory
[Name]

Benzoic acid, 5-[2-[4-[2-(2,4-diamino-5-methylphenyl)diazenyl]phenyl]diazenyl]-2-hydroxy-
[CAS]

739301-85-0
[Synonyms]

Benzoic acid, 5-[2-[4-[2-(2,4-diamino-5-methylphenyl)diazenyl]phenyl]diazenyl]-2-hydroxy-
[Molecular Formula]

C20H18N6O3
[MOL File]

739301-85-0.mol
[Molecular Weight]

390.4
Chemical PropertiesBack Directory
[Boiling point ]

733.9±60.0 °C(Predicted)
[density ]

1.43±0.1 g/cm3(Predicted)
[pka]

2.72±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

NSC45586 is an inhibitor of pleckstrin homology domain and leucine-rich repeat protein phosphatase (PHLPP). NSC45586 targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 can activate AKT in neurons[1].
[References]

[1] Jackson TC, et, al. Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes. J Pharmacol Exp Ther. 2013 Nov;347(2):516-28. DOI:10.1124/jpet.113.206888
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