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748145-12-2

748145-12-2 Structure

748145-12-2 Structure
IdentificationBack Directory
[Name]

5H-Pyrazolo[3,4-b]quinolin-5-one, 1,4,6,7,8,9-hexahydro-3,7,7-trimethyl-4-(2-pyridinyl)-
[CAS]

748145-12-2
[Synonyms]

WAY-606954
3,7,7-Trimethyl-4-(pyridin-2-yl)-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one
5H-Pyrazolo[3,4-b]quinolin-5-one, 1,4,6,7,8,9-hexahydro-3,7,7-trimethyl-4-(2-pyridinyl)-
[Molecular Formula]

C18H20N4O
[MOL File]

748145-12-2.mol
[Molecular Weight]

308.38
Chemical PropertiesBack Directory
[Boiling point ]

516.1±50.0 °C(Predicted)
[density ]

1.28±0.1 g/cm3(Predicted)
[pka]

15.59±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

GSK3-IN-9 (Compound 0713) is a selective glycogen synthase kinase 3 (GSK3) inhibitor. GSK3-IN-9 Fragile X syndrome, attention deficit hyperactivity disorder (ADHD), childhood seizure, intellectual disability, diabetes, acute myeloid leukemia (AML), autism, and psychiatric disorder[1].
[References]

[1] Edward Scolnick, et al. Uses of paralog-selective inhibitors of gsk3 kinases. US20160375006A1. 2016 December 29.
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