ChemicalBook--->CAS DataBase List--->74817-61-1

74817-61-1

74817-61-1 Structure

74817-61-1 Structure
IdentificationBack Directory
[Name]

Murabutide
[CAS]

74817-61-1
[Synonyms]

Murabutide
N-acetylmuramyl-alanylglutamine-n-butyl ester
D-Glutamine, N-(N-acetylmuramoyl)-L-alanyl-, butyl ester
[Molecular Formula]

C23H40N4O11
[MDL Number]

MFCD00867587
[MOL File]

74817-61-1.mol
[Molecular Weight]

548.58
Chemical PropertiesBack Directory
[Boiling point ]

971.7±65.0 °C(Predicted)
[density ]

1.278±0.06 g/cm3(Predicted)
[pka]

13.13±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Murabutide is a safe synthetic immunomodulator. Murabutide can reduce CD4 and CCR5 receptor expression and secrete high levels of beta-chemokines. Murabutide enhances nonspecific resistance against viral infections. Murabutide did not affect virus entry, reverse transcriptase activity or early proviral DNA formation in the cytoplasm of infected cells[1].
[References]

[1] E C Darcissac, et al. The synthetic immunomodulator murabutide controls human immunodeficiency virus type 1 replication at multiple levels in macrophages and dendritic cells. J Virol. 2000, 74, 17. DOI:10.1128/jvi.74.17.7794-7802.2000
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