| Identification | Back Directory | [Name]
U-58,431 | [CAS]
75533-14-1 | [Synonyms]
U-58,431
Antibiotic U-58431
(1R,3R,4R,9R)-6-Amino-3,4,5,8-tetrahydro-4,9-dihydroxy-3-methyl-5,8-dioxo-1,4-ethano-1H-2-benzopyran-7-carboxamide | [MOL File]
75533-14-1.mol |
| Hazard Information | Back Directory | [Description]
U-58431 is an antibiotic isolated from the fermentation broth of Streptomyces helicus. | [Uses]
Sarubicin A (U-58431) is an antibiotic that inhibits Gram-positive and Gram-negative bacteria and has antitumor activity[1][2]. | [References]
[1] Wang H, et al. Sarubicinols A–C, Cytotoxic Benzoxazoles from a Streptomyces[J]. Journal of Natural Products, 2022, 85(4): 1167-1173. DOI:10.1021/acs.jnatprod.1c00820
[2] Slechta L, et al. Fermentation, Isolation, Characterization And Structure Of Antibiotic U-58, 431[J]. The Journal of Antibiotics, 1980, 33(9): 919-923. DOI:10.7164/antibiotics.33.919 |
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