| Identification | Back Directory | [Name]
(S)-Benzyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-ylcarbamate | [CAS]
769922-77-2 | [Synonyms]
Z-PHE-BT
(S)-N-Z-1-Benzotriazolylcarbonyl-2-phenylethylamine
(S)-Benzyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-ylcarbamate
Carbamic acid, N-[(1S)-2-(1H-benzotriazol-1-yl)-2-oxo-1-(phenylmethyl)ethyl]-, phenylmethyl ester | [Molecular Formula]
C23H20N4O3 | [MDL Number]
MFCD22200497 | [MOL File]
769922-77-2.mol | [Molecular Weight]
400.43 |
| Chemical Properties | Back Directory | [Melting point ]
143-150°C | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
solid | [pka]
10.32±0.46(Predicted) | [Major Application]
peptide synthesis | [InChI]
1S/C23H20N4O3/c28-22(27-21-14-8-7-13-19(21)25-26-27)20(15-17-9-3-1-4-10-17)24-23(29)30-16-18-11-5-2-6-12-18/h1-14,20H,15-16H2,(H,24,29)/t20-/m0/s1 | [InChIKey]
YKOJLKRZEWWYIH-FQEVSTJZSA-N | [SMILES]
O=C(N[C@@H](Cc1ccccc1)C(=O)n2nnc3ccccc23)OCc4ccccc4 |
| Safety Data | Back Directory | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Uses]
Benzotriazole amino acids, or aminoacylbenzotriazolides, are versatile reagents for synthesizing peptides as well as their mimetics and conjugates. Benzotriazole amino acids have been used for the preparation of diverse derivatives including:
- Polypeptidal benzotriazolides
- Peptidomimetics, such as aminoxypeptides, depsipeptides and heterocyclic peptidomimetics
- Tagged peptides and peptidomimetics, particularly those with fluorescent labels
- N, O, S, and C linked peptide conjugates
| [reaction suitability]
reaction type: solution phase peptide synthesis |
|
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Energy Chemical
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Sigma-Aldrich
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