| Identification | Back Directory | [Name]
TROPONIN I | [CAS]
77108-40-8 | [Synonyms]
TNI
HCTNL
TROPONIN I
TROPONIN I, HUMAN
TROPONIN I (CARDIAC)
TROPONIN I (SKELETAL)
TROPONIN I, HUMAN HEART
TROPONIN I-CARDIAC, HUMAN
TROPONIN I, HUMAN CARDIAC
TROPONIN I-SKELETAL, HUMAN
TROPONIN I, HUMAN SKELETAL
troponin I from human heart
TroponinI from human heart,Tn-I
TROPONIN I (HUMAN CARDIAC MUSCLE)
TROPONIN I (HUMAN SKELETAL MUSCLE)
Recombinant Human Cardiac Troponin-I
Troponin I from human heart lyophilized powder | [Molecular Formula]
NULL | [MDL Number]
MFCD00213059 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
urea/Tris buffer (0.02 M Tris, HCl, pH 7.5, 7 M urea, 5 mM EDTA, 15 mM 2-mercaptoethanol): 1mg/mL | [form ]
lyophilized powder | [biological source]
human heart | [Water Solubility ]
water: 5vial/mL, clear, colorless |
| Hazard Information | Back Directory | [Uses]
Troponin I from human heart can be used in studies whether the actin and aldolase can protect rabbit muscle lactate dehydrogenase inhibition by ascorbate or not. | [General Description]
Native troponin I purified from human heart. Inhibitory subunit of troponin that binds to actin in the absence of Ca2+, thus inhibiting the ATPase activity of actomyosin. Presence of Tnl in plasma has been used for early detection of myocardial infarction. Useful as a standard in immunoassay and as an immunogen for anti-sera production. Also useful as a tracer for iodination. | [Biochem/physiol Actions]
Troponin I interacts with tropomyosin for regulating the contraction of striated muscle in a calcium-dependent manner. Additionally, Troponin I can also inhibits actomyosin ATPase and serves as a selective and potent inhibitor of angiogenesis in vivo and in vitro and of tumor metastasis in vivo. |
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